A huge influence on Elvis Presley, Johnny Cash, Ray Charles and Jimi Hendrix, Sister Rosetta Tharpe was a legend in her time, bringing fierce guitar-playing and swing to gospel music. Tharpe was the queen of "race records" in the 30’s and 40’s, a woman who played guitar as passionately as Clapton, who performed mornings at churches and evenings at the Cotton Club, who was a big enough star to fill a baseball stadium for her third wedding, but ended up buried in an unmarked grave in Philadelphia. Marie and Rosetta chronicles Sister Rosetta’s first rehearsal with a young protégée, Marie Knight, as they prepare to embark on a tour that would establish them as one of the great duet teams in musical history.